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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LYAR
All Species:
41.82
Human Site:
Y58
Identified Species:
65.71
UniProt:
Q9NX58
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NX58
NP_001139197.1
379
43615
Y58
C
I
S
E
D
Q
K
Y
G
G
K
G
Y
E
G
Chimpanzee
Pan troglodytes
XP_001153728
379
43666
Y58
C
I
S
E
D
Q
K
Y
G
G
K
G
Y
E
G
Rhesus Macaque
Macaca mulatta
XP_001096675
379
43478
Y58
C
I
S
E
D
Q
K
Y
G
G
K
G
Y
E
G
Dog
Lupus familis
XP_536242
380
42964
Y58
C
I
S
E
E
Q
K
Y
G
G
K
G
Y
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q08288
388
43717
Y58
C
I
S
E
G
Q
K
Y
G
G
K
G
Y
E
A
Rat
Rattus norvegicus
Q6AYK5
386
43662
Y58
C
I
S
E
D
Q
K
Y
G
G
K
G
Y
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511111
391
45222
Y58
C
I
S
E
D
Q
K
Y
G
G
K
A
Y
E
A
Chicken
Gallus gallus
XP_420792
364
42082
Y58
C
V
T
E
D
E
K
Y
G
G
K
D
F
E
A
Frog
Xenopus laevis
NP_001086609
360
41600
Y58
C
I
S
E
D
Q
K
Y
G
G
K
A
F
E
A
Zebra Danio
Brachydanio rerio
NP_956973
320
37238
Y58
C
I
S
E
D
Q
K
Y
G
G
R
D
F
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610573
281
32090
D37
D
K
N
V
S
C
M
D
C
L
K
D
F
Y
G
Honey Bee
Apis mellifera
XP_623803
246
28455
Nematode Worm
Caenorhab. elegans
Q09464
253
28497
C9
V
F
F
S
C
N
N
C
G
E
A
C
K
K
N
Sea Urchin
Strong. purpuratus
XP_780603
1141
125640
Y59
C
I
S
E
D
Q
K
Y
G
G
K
G
Y
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37263
153
17720
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
97.3
76.8
N.A.
72.6
74.8
N.A.
62.9
55.6
53.2
43.7
N.A.
27.1
26.9
29.8
20.2
Protein Similarity:
100
98.9
98.6
85.5
N.A.
83.5
86.5
N.A.
76.2
71.7
69.9
64.3
N.A.
46.9
40.1
44.8
28.1
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
86.6
60
80
66.6
N.A.
13.3
0
6.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
86.6
86.6
86.6
86.6
N.A.
26.6
0
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
7
14
0
0
47
% A
% Cys:
74
0
0
0
7
7
0
7
7
0
0
7
0
0
0
% C
% Asp:
7
0
0
0
60
0
0
7
0
0
0
20
0
0
0
% D
% Glu:
0
0
0
74
7
7
0
0
0
7
0
0
0
60
0
% E
% Phe:
0
7
7
0
0
0
0
0
0
0
0
0
27
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
80
74
0
47
0
0
34
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
0
74
0
0
0
74
0
7
7
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
7
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
67
0
0
0
0
0
0
0
14
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
0
0
67
7
7
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
74
0
0
0
0
54
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _